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Epigenetics of Vascular Formation during Zebrafish Hindbrain Development
http://hdl.handle.net/10487/00016654
http://hdl.handle.net/10487/00016654160c62b7-3f53-4ae0-b6c6-0804d6f7d6db
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
03 Epigenetics of Vascular Formation during Zebrafish Hindbrain Development (1.8 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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| 公開日 | 2021-01-08 | |||||
| タイトル | ||||||
| タイトル | Epigenetics of Vascular Formation during Zebrafish Hindbrain Development | |||||
| 言語 | en | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | zebrafish | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | hindbrain | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | angiogenesis | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | histone methylation | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 著者 |
Fujita, Misato
× Fujita, Misato× Izumi, Susumu |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | The brain circulatory system is essential for the survival and development of the central nervous system in all vertebrates. Brain vessels form in a reproducible and evolutionarily conserved manner. In zebrafish, hindbrain vessels develop independently of the shear stress of blood flow but are regulated genetically. Epigenetics is another regulatory system regulating gene activation, but the epigenetic contribution to angiogenesis remains unclear. Here, we examine expression patterns of genes involved in SET1/mixed lineage leukemia (MLL) histone methyltransferase complexes. All mRNAs we tested as orthologs of molecules in the MLL complex were expressed throughout the central nervous system, including the hindbrain. We also show immunofluorescent staining of retinoblastoma-binding protein 5 (RBBP5) protein in the dorsal hindbrain, suggesting the possibility of differences in epigenetic state along the dorsalventral axis. Finally, we demonstrate histone methylation with non-methylated, dimethylated, and trimethylated types. | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Full-Length Paper | |||||
| 内容記述 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | By a grant from Research Institute for Integrated Science, Kanagawa University | |||||
| 書誌情報 |
en : Science Journal of Kanagawa University 巻 31, p. 15-20, 発行日 2020-10-30 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 1880-0483 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA12068302 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 出版者 | ||||||
| 出版者 | 神奈川大学総合理学研究所 | |||||
| 資源タイプ | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Departmental Bulletin Paper | |||||
