{"created":"2023-05-15T11:51:33.639166+00:00","id":13567,"links":{},"metadata":{"_buckets":{"deposit":"09b59948-f584-45bb-b9b9-7ba1105cc958"},"_deposit":{"created_by":10,"id":"13567","owners":[10],"pid":{"revision_id":0,"type":"depid","value":"13567"},"status":"published"},"_oai":{"id":"oai:kanagawa-u.repo.nii.ac.jp:00013567","sets":["376:377:378:1311"]},"author_link":["33600","35216","33600","35216"],"item_3_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-10-30","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"20","bibliographicPageStart":"15","bibliographicVolumeNumber":"31","bibliographic_titles":[{"bibliographic_title":"Science Journal of Kanagawa University","bibliographic_titleLang":"en"}]}]},"item_3_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The brain circulatory system is essential for the survival and development of the central nervous system in all vertebrates. Brain vessels form in a reproducible and evolutionarily conserved manner. In zebrafish, hindbrain vessels develop independently of the shear stress of blood flow but are regulated genetically. Epigenetics is another regulatory system regulating gene activation, but the epigenetic contribution to angiogenesis remains unclear. Here, we examine expression patterns of genes involved in SET1/mixed lineage leukemia (MLL) histone methyltransferase complexes. All mRNAs we tested as orthologs of molecules in the MLL complex were expressed throughout the central nervous system, including the hindbrain. We also show immunofluorescent staining of retinoblastoma-binding protein 5 (RBBP5) protein in the dorsal hindbrain, suggesting the possibility of differences in epigenetic state along the dorsalventral axis. Finally, we demonstrate histone methylation with non-methylated, dimethylated, and trimethylated types.","subitem_description_type":"Abstract"}]},"item_3_description_40":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Departmental Bulletin Paper","subitem_description_type":"Other"}]},"item_3_description_5":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"Full-Length Paper","subitem_description_type":"Other"},{"subitem_description":"By a grant from Research Institute for Integrated Science, Kanagawa University","subitem_description_type":"Other"}]},"item_3_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"神奈川大学総合理学研究所"}]},"item_3_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA12068302","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_8":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1880-0483","subitem_source_identifier_type":"ISSN"}]},"item_3_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Fujita, Misato"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Izumi, Susumu"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-01-08"}],"displaytype":"detail","filename":"03 Epigenetics of Vascular Formation during Zebrafish Hindbrain Development.pdf","filesize":[{"value":"1.8 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"03 Epigenetics of Vascular Formation during Zebrafish Hindbrain Development","url":"https://kanagawa-u.repo.nii.ac.jp/record/13567/files/03 Epigenetics of Vascular Formation during Zebrafish Hindbrain Development.pdf"},"version_id":"f0f33783-18e9-4ed4-ac5e-96069d9a602b"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"zebrafish","subitem_subject_scheme":"Other"},{"subitem_subject":"hindbrain","subitem_subject_scheme":"Other"},{"subitem_subject":"angiogenesis","subitem_subject_scheme":"Other"},{"subitem_subject":"histone methylation","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Epigenetics of Vascular Formation during Zebrafish Hindbrain Development","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Epigenetics of Vascular Formation during Zebrafish Hindbrain Development","subitem_title_language":"en"}]},"item_type_id":"3","owner":"10","path":["1311"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-01-08"},"publish_date":"2021-01-08","publish_status":"0","recid":"13567","relation_version_is_last":true,"title":["Epigenetics of Vascular Formation during Zebrafish Hindbrain Development"],"weko_creator_id":"10","weko_shared_id":-1},"updated":"2023-06-19T02:08:58.052321+00:00"}