2026-03-15T05:27:45Z https://kanagawa-u.repo.nii.ac.jp/oai

oai:kanagawa-u.repo.nii.ac.jp:00006912 2023-05-15T15:45:39Z 376:377:378:555

Development of a Novel Method for Immobilization of DNA Applied for DNA Chip DNAチップのための新規DNA固定化法の開発(2004年度神奈川大学総合理学研究所助成共同研究) 山口, 和夫 Yamaguchi, Kazuo 塩野, 博文 Shiono, Hirofumi active ester silane coupling agent silicon wafer immobilized amine DNA chip Silane coupling agent 1 containing active ester was synthesized and applied for surface modification of silicon wafer. An active ester immobilized using 1 was reacted with a nonanucleotide containing an amino group at the 5'-terminal labeled with a fluorescent reagent followed by observation of the surfaces using a fluorescence microscope. The result showed that the coupling agent was potential for novel compounds for immobilization of DNA. departmental bulletin paper 神奈川大学 2005-05-25 VoR application/pdf Science Journal of Kanagawa University 16 99 100 AA12068302 1880-0483 https://kanagawa-u.repo.nii.ac.jp/record/6912/files/SJKU Vol 16 2005 99-100.pdf http://hdl.handle.net/10487/1434 https://kanagawa-u.repo.nii.ac.jp/records/6912 jpn