2026-03-06T02:37:12Z https://kanagawa-u.repo.nii.ac.jp/oai

oai:kanagawa-u.repo.nii.ac.jp:00006929 2023-05-15T15:45:18Z 376:377:378:556

光に安定な貴金属カルボン酸塩錯体の構造多様性と生理活性(2005年度神奈川大学総合理学研究所助成共同研究) A Variety of Ag-O Bonding Modes and Antimicrobial Activities of Light-Stable Coinage Metal Complexes with Carboxylate Ligands 野宮, 健司 Nomiya, Kenji 力石, 紀子 Chikaraishi, Kasuga Noriko 野口, 龍介 Noguchi, Ryusuke 木村, 卓央 Kimura, Takao silver(I) complexes 2-pyrrolidone-5-carboxylic acid triphenylphosphine Ag-O bonding modes crystal and molecular structures antimicrobial activities Using light-stable dimeric silver(I) carboxylate precursors {[Ag(Hpyrrld)]_2}_n formed with chiral and racemic forms of 2-pyrrolidone-5-carboxylic acid (H_2pyrrld) ligand, six novel light-stable, triphenylphosphinesilver(I) complexes consisting of both a hard Lewis base (O atom) and a soft Lewis base (P atom) were prepared, i.e. [Ag_2(R-Hpyrrld)_2(H_2O)(PPh_3)_2]・H_2O 1,[Ag(R-Hpyrrld)(PPh_3)_2]_2 2, [Ag_2(S-Hpyrrld)_2(H_2O)(PPh_3)_2]・H_2O 3, [Ag(S-Hpyrrld)(PPh_3)_2]_2 4,{[Ag(R,S-Hpyrrld)(PPh_3)]_2}_n 5 and [Ag(R,S-Hpyrrld)(PPh_3)_2] 6. Their solid-state and solution structures were unequivocally characterized with elemental analysis, TG/DTA, FTIR, X-ray structure analysis, molecular weight measurements in EtOH with the vaporimetric method, solution (^1H, ^<13>C, ^<31>P) NMR and solid-state ^<31>P CPMAS NMR spectroscopy. Two sets of enantiomeric complexes were isolated as (1 and 3) and (2 and 4). X-ray crystallography revealed that these complexes possessed different Ag-O bonding modes, depending on the number of PPh_3 ligands and the chirality of the Hpyrrld ligand. Complexes 1-6 behaved as a monomeric species in EtOH and CD_2Cl_2. Antimicrobial activites by silver(I) complexes in the water-suspension system against selected bacteria, yeast and molds were significantly correlated with the number of coordinating PPh_3 ligands per silver(I) atom in the complexes. 神奈川大学 2006-05-25 jpn departmental bulletin paper VoR http://hdl.handle.net/10487/1447 https://kanagawa-u.repo.nii.ac.jp/records/6929 AA12068302 1880-0483 Science Journal of Kanagawa University 17 85 88 https://kanagawa-u.repo.nii.ac.jp/record/6929/files/kana-2-2-0013.pdf application/pdf 1.1 MB 2018-11-20